Phase-out of CFC Consumption in the Manufacture of Aerosol Metered-dose Inhalers (MDIs) in the Russian Federation

The objectives of this project are (a) through appropriate technology transfer, to phase-out the consumption of 212 ODP tones of CFC-11 and CFC-12 (2010) used in the manufacture of Aerosol Metered-Dose Inhalers (MDIs) in the Russian Federation (RF) and (b) to reduce future GHG emissions by approx. 1.7 MMT CO2 t/equivalent, by introducing, through technology transfer a lower GHG propellant. The two MDI companies in the RF will require technology transfer from one, or more, established multinational enterprises that have experience in the development and manufacture of MDIs using CFC-free technologies, and who have the right to transfer such technology to the Russian Federation (RF) without infringement of any intellectual property related to either the drug molecule, the method of formulation, the design of the metering valve or actuator or the filling process. This proposal addresses the requirements for conversion of a manufacturing facility currently using CFCs to manufacture MDIs with CFC-free propellant.