This publication is a product of the GEF-funded Food and Agriculture Organization project ‘Decision Support for Mainstreaming and Scaling Out Sustainable Land Management (DS-SLM)’ which has developed a decision support framework (DSF). The DSF integrates experience from work with land degradation and sustainable land management (SLM) into an overall strategy for mainstreaming and scaling out SLM at different spatial and temporal scales. This publication serves as a step-by-step guide for the application and implementation of the DSF during planning, design, and implementation of SLM interventions. It includes elements – both in its modules and proposed tools and methods – which can support countries in pursuing land degradation neutrality.